Question

which of the following statements about the wobble hypothesis is incorrect A) a mn of 32 trna are required to translate all 61 codons B) the 5' end of the ant codon can have flexible bnding partners C) bindng of anti codon seq to the 3' end of the codon is flexible D) there are fewer types of codons encoding all the amno acds n one cell nucleus compared to the type of amnoacyl tRNAs present in that cell

Answer 1

Option C is the correct answer. According to Wobble hypothesis the minimum requirement to recognize all possible codons is 32. (31 for amino acids and one for stop codon). The 5'end of anticodon have flexible binding partners. For example if third nucleotide of codon is A, then it can base pair with U or I (inosine). In the same way G can base pair with either C or U. Due to this flexibility fewer types of codons encodes all the amino acids.

The 3' end of codon is not flexible rather the 5' end of anticodon is flexible and thus the binding of anticodon sequence to the 3'end of the codon is not flexible.