Question

During DNA replication, methylation is A. maintained by a semiconservative process. B. erased and then a...

During DNA replication, methylation is

A. maintained by a semiconservative process.

B. erased and then a maintenance methylase adds back methyl groups to both the template and the newly synthesized strand.

C. not maintained; replication results in hemimethylated progeny DNA.

D. erased and then a maintenance me

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Answer #1

option c

Methylation is the process of addition of methyl groups to specific nucleotides on DNA molecule. Both the strands of parental DNA molecules are methylated.

After the process of semi-conservative replication of DNA, the daughter DNA molecule consists of one parental strand which is methylated and one daughter strand which is not methylated. Therefore first option is incorrect because methylation is not maintained by semi-conservative process.

After the process of replication is completed, specific methylases come into play and lead to the addition of methyl groups on daughter DNA strand.

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