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Where do you need ribonucleotides during DNA replication? HINT: They play TWO different roles

Where do you need ribonucleotides during DNA replication? HINT: They play TWO different roles

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Ans. The requirement of RNA ribonucleotides during DNA replication are as follow-

#I. As RNA primer: DNA polymerase can’t synthesize new DNA strands on their own, they only extend a previously synthesised RNA primer by primase. The RNA primers are polymer of ribonucleotides.

#II. As energy molecule: ATP, the primary energy molecule for cellular processes, is also a ribonucleotide. ATP is required during unwinding of double stranded DNA helix by topoisomerases and DNA B helicase.

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