Question

what about a polypeptide would cause it to be directed to the ER for translation?

what about a polypeptide would cause it to be directed to the ER for translation?

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

mRNA of the polypeptide that has to be transported to ER produces a signal peptide in the N- terminal that comes out of the ribosome during translation. This signal peptide is recognised by a protein called SRC ( Signal recognition complex). SRC bound to signal peptide along with the ribosome binds to the SRC receptor on the surface of the ER situated next to translocon. The signal peptide is inserted in to the ER lumen where it is cleaved by the signal peptidase and protein synthesis is carried on inserting the produced polypeptide in the ER lumen from where it is transported to desired location.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
TRANSLATION: Describe the process of translation at the ribosome. Describe how ribosomal RNA, messenger RNA and...
TRANSLATION: Describe the process of translation at the ribosome. Describe how ribosomal RNA, messenger RNA and transfer RNA all participate in the construction of a polypeptide chain. Explain what the signal recognition particle (SRP) of a newly formed protein will do.
4-3.  To demonstrate an understanding of translation elongation, we’ll start somewhere in the middle of translation of...
4-3.  To demonstrate an understanding of translation elongation, we’ll start somewhere in the middle of translation of a polypeptide.  At this moment, the entire ribosome (the small and large subunits) is bound to the mRNA, and there is a tRNA bound at the P-site.  Attached to the 3’-end of this tRNA is the start of the polypeptide- Amino-Met-Leu-Ser-Ala-Phe-tRNA At this starting point, there is no other tRNA bound to the ribosome, and the next codon is 5’-UGG-3’ When the next tRNA binds to...
1. Which of the following statements about the process of translation is INCORRECT? a. Translation ends...
1. Which of the following statements about the process of translation is INCORRECT? a. Translation ends when the ribosome encounters a stop codon. b. The polypeptide might be attached to a tRNA found either in the “A” site or in the “P” site of the ribosome. c. Ribosomes and initiation factors begin translation by locating the promoter. d. An “empty” tRNA (attached neither to an amino acid nor to a polypeptide) might be found either in the “E” or in...
what happens during the Initiation stage of translation ? a) ribosomes reads mRNAone codon at a...
what happens during the Initiation stage of translation ? a) ribosomes reads mRNAone codon at a time b)polypeptide is released from the ribosome C) ribosome breaks up into its subunits D)ribosomalsubunits come together and blind to mRNA
What would happen to TRANSLATION if there was a mutation such that a UGA codon was...
What would happen to TRANSLATION if there was a mutation such that a UGA codon was changed to UCA? Explain your reasoning.
1. In chapter 2, you learned that a polypeptide in solution usually folds spontaneously into its...
1. In chapter 2, you learned that a polypeptide in solution usually folds spontaneously into its proper three-dimensional shape. The driving force for this folding is the tendency to achieve the most favored thermodynamic conformation. A folded polypeptide can be induced to unfold (i.e. will undergo denaturation) if the solution is heated or made acidic or alkaline. The denatured polypeptide is a random structure, with many possible conformations. a. What is the sign of ∆G for the folding process? What...
What are the implications of translation exposure? Why would firms not hedge against it? What are...
What are the implications of translation exposure? Why would firms not hedge against it? What are the benefits if they do? Thanks!
What would happen to TRANSLATION if there was a nonsense mutation in the 5’ untranslated region...
What would happen to TRANSLATION if there was a nonsense mutation in the 5’ untranslated region of an mRNA? Explain your reasoning
What factors would cause one to increase the withdrawal rate? What factors would cause one to...
What factors would cause one to increase the withdrawal rate? What factors would cause one to decrease the withdrawal rate?
What effect would a non-hydrolysable ATP analogue have on translation elongation? Why?
What effect would a non-hydrolysable ATP analogue have on translation elongation? Why?
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT