Question

What is the difference between the type of reactions catalyzed by isomerases (narrowly defined) and mutases?...

What is the difference between the type of reactions catalyzed by isomerases (narrowly defined) and mutases? Draw a reaction from glycolysis that is an example of each.

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Answer #1

Isomerase is a class of enzymes that changes the form of one molecule into other forms by rearrangement of atoms within a molecule. Isomerase could be racemase, epimerase, cis-trans isomerase, etc. While Mutase is a part of isomerase that catalyses those reactions in which there's a change in the position of a group in a molecule which changes it to some other form. Eg: phosphoglycerate mutase which changes 3-phosphoglycerate to 2-phosphoglycerate, by just changing the position of the phosphate group from 3rd carbon to 2nd.

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