Question

Which part of the nervous system (peripheral or central) typically regenerates more effectively? What are some important differences between the myelinating cells in each area that support or inhibit regeneration ?

Answer 1

Peripheral nervous system has an intrinsic ability for repair and regeneration while CNS is incapable of self repair and regeneration

Differences are as follows:-

• In PNS ability of cells to repair and regenerate after Injury is programmed while in CNS this programming within the cells is absent
• Growth promoting factors are present in the cells of PNS while growth inhibiting factors are present in CNS which causes inhibition of regeneration. It includes specific proteins in CNS myelin