Question

During prophase of mitosis, each replicated chromosome attaches to a different microtubule on the mitotic spindle apparatus

Select one:

a. False

b. True

---------

During the S-phase of the cell cycle, each chromosome has multiple replication bubbles

Select one:

a. False

b. True

-------

Growth factors affect the cell cycle by binding to

Select one:

a. Receptor tyrosine kinases (RTK)

b. Rb proteins

c. Intracellular receptors

d. Cyclin/CDK complexes

e. G protein coupled receptors (GPCR)

----------

Growth factors are typically

Select one:

a. Synaptic signals

b. Autocrine signals

c. Cell-cell contact signals

d. Endocrine signals

e. Paracrine signals

---------

How many checkpoints does a typical cell cycle have?

Select one:

a. 17

b. 5

c. 12

d. 3

e. 2

Answer 1

1. False as the replicated chromosomes get attached to the microtubules at the boundary of metaphase and anaphase transition. not in prophase.

2.. True, During replication is S phase , multiple bubbles are formed in order to replicate the DNA earlier.

3. Option a, the growth factors binds with receptor tyrosine kinase (RTK) and affect the cell cycle.

4. Option d - growth hormones act as endocrine signals as they work over a long distance.  

5. a typical cell cycle has following 3 check points -

a. G 1 check point

b. G2 check point

c. Spindle check point at the boundary of metaphase to anaphase transition