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Draw a picture showing the path a secreted protein takes from synthesis until it exits the...

Draw a picture showing the path a secreted protein takes from synthesis until it exits the cell.

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Answer #1

Steps in the secretion of a protein:
1. Transcription of the gene in the nucleus
2. Export of mRNA into the cytoplasm
3. Translation by ribosomes on RER
4. Transport into the ER lumen and post-translational modifications
5. Transport into the Golgi lumen and post-translational modifications
6. Production of secretory vesicles from the Golgi trans-face
7. The fusion of vesicles to the plasma membrane and secretion of the protein

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