Question

You perform an experiment to visualize the pigments in wild type and mutant fruit fly eyes and summarize the results in the following table. Indicate precisely where the mutation(s) will be located and explain the reason(s) underlying the eye colour of the mutant. You will need to examine these results and the chart outlining the pteridine synthetic pathways below, and recall your knowledge of the different pathways for fruit fly eye pigment production

Pigment	Colour	Rf	Wild-Type	White	Blue	Brown	Ruby
Isosepiapterin	yellow	0.50	+	-	+	-	++
Biopterin	blue	0.41	+	-	-	-	++
2-amino-4-hydroxypteridine	blue	0.31	+	-	+	-	++
Sepiapterin	yellow	0.26	+	-	+	-	++
Xanthopterin	green-blue	0.18	+	-	++++	-	++
Isoxanthopterin.	violet-blue	0.13	+		-	-	++
Drosopterin	orange	0.05	+	-	+	-	++

Mutant Fruit Fly	Mutation / Explanation for Eye Colour
White
Blue
Brown
Ruby

Answer 1