in the resting state of a nerve cell,
- The inside of the cell has more number of K+ ions and less Na+
ions
- The outside contains more Na+ and less K+ ions
- The cytosol also contains a high concentration of
anions--phosphate ions and negatively charged proteins.
In case of depolarisation
- The action potential occurs and the Na+ channels open.
- There is a sudden influx of the sodium ions into the cytosol
due to the concentration gradient
- This causes a sudeen increase in the membrane potential.
- The K+ concentration will be higher inside the cell
the potential increases and reaches a state in which the K+
channels are opened .The k+ ions move out of the cell and the
membrane potential gradually drops.This is repolarisation