Question

How can argonaute proteins be used in genetic engineering/biotechnology? Can you give some examples?

How can argonaute proteins be used in genetic engineering/biotechnology? Can you give some examples?

Homework Answers

Answer #1

Argonaute proteins are highly specified binding molecules that accomodates the small RNA components(micro RNAs), they regulate gene expression and defend against foreign pathogen invasion by small RNA- mediated gene silencing pathways. they play a major role in RNA silencing process, as essential component of RNA induced silencing complex called  RNA interference. argonaute proteins bind different classes of small non-coding RNAs. small RNAs guide argonaute proteins to their targets through base pairing, that leads to translation inhibition.

examples of argonaute proteins include,
Ago1-4(ago like family) for homosapiens host
PIWI 1-4(PIWI like family) for homosapiens host
Ago 1-10(ago like family) for arabidopsis thalina host

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