Question

can someone please answer the following questions with the correct options. thank you

16. some of your duplicate data may have been very variable. What modification would you suggest to get round this problem?

a. Removing obviously wring duplicate data from the analysis

b. with two widely divergent cpm counts in a duplicate set, exclude the single value that doesn’t fit in with the rest of the data and keep the other

c. Treating the erroneous duplicate data as an outlier

d. Have three assay tubes at each deprenyl concentration not two.

19. why it Carbidopa used in the treatment of Parkinson’s disease?

a. it is a COMT inhibitor which increases the synaptic levels of dopamine

b. It is a MAO-B inhibitor which increases the synaptic levels of dopamine

c. It inhibits dopa decarboxylation in the brain

d. It binds to dopamine receptors in the absence of dopamine

e. It preserves L-Dopa in the periphery by blocking dopa decarboxylase

Answer 1

16. If you have too much variability in your duplicates, its always a good idea to have triplicates instead of duplicates. This way you will know which two values out of three are significant ones and which one is the outlier. Therefore, your answer is (d)

19. Carbidopa is an inhibitor of DOPA decarboxylase. Since the precursor of dopamine, Levodopa is converted to dopamine via the action of a naturally occurring enzyme called DOPA decarboxylase in the blood stream before it reaches the brain. Therefore, a DOPA decarboxylase inhibitor is added in combination to allow Levodopa to reach the brain and not get lost in the blood stream.Therefore, your answer is (c)