Question

What two properties of an enzyme does the catalytic efficiency reflect?Why is this value worth determining?

Answer 1

Enzymes are biological catalysts.It accelerate reaction toward equilibrium without changing the position of equilibrium. Catalysts remain unchanged in the process.

Enzymes achieve chemical transformations through many different mechanisms, they exhibit a common set of physical principles. The review focuses on the role that computation has played and will continue to play in unravel complexities of enzyme catalysis. Even within focused goal, we are only able to cover a small sampling of the theoretical contributions to this field and concentrate on the work from our own group to illustrate the fundamental concepts underlying enzyme catalysis.