Question

A) How many protons are required for ATP synthase to rotate 360 degrees? Explain! B) How...

A) How many protons are required for ATP synthase to rotate 360 degrees? Explain!

B) How many ATPs are produced in a 360-degree rotation of ATP synthase? Explain!

C) How does this account for the fact that electrons from 2 NADH molecules results in the production of 5 ATP molecules? Explain!

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Answer #1

A)

  • there are 10 subunits in the c ring of ATP synthase
  • Every subunit releases 1 proton into the matrix when it turns 360 degree
  • Hence totally 10 protons are released into the matrix by 10 subunits for every 360 degree turn

B)

  • Every 120 degree catalyses the formation of 1ATP
  • Every 1 degree catalyses the formation of 1/120 ATP
  • Every 360 degree catalyses the formation of 1/120 X360 ATP=3ATP
  • Therefore total 3 ATPs are produced

C)

  • Each NADH2 yields 2.5 ATP
  • Therefore 2 NADH2 yields 2.5 X2= 5 ATP
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