Question

The growing peptide chain is found in which region of the large ribosomal subunit? Select one:...

The growing peptide chain is found in which region of the large ribosomal subunit?

Select one:

a. A site

b. P site

c. E site

d. It is found in the small ribosomal subunit

Homework Answers

Answer #1

Answer. (B) P site

Once the peptidyl transferase reaction has occurred, the new peptidyl-tRNA in the A-site is translocated to the P-site as the ribosome move exactly 3 nucleotides along the mRNA molecule, going in the 5'-3' direction. This movement is referred to as translocation. This step is mediated by the elongation factor EF-G and is driven by splitting a GTP to GDP.

During elongation process these events repeat. Again, the correct aminiacyl-tRNA is loaded into the A-site of the ribosome as dictated by the A-site codon. A peptide bond is formed between the aminiacyl-tRNA in the A-site and the growing peptide chain is attached to the peptidyl-tRNA in the P-site​.

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