Question

______ Is an inherited disorder of the lungs a genetic mutation caused the lungs to produce...

______ Is an inherited disorder of the lungs a genetic mutation caused the lungs to produce a thick mucous that clogs air passages

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Answer #1

Cystic fibrosis is an autosomal recessive disorder that occurs due to mutations in both the copies of the gene (located on chromosome 7) for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The CFTR protein is a chloride ion channel involved in the production of mucus, sweat and digestive fluids. Defective ion transport leads to dehydration that causes thickening of the secretions. Thus in the lungs, the thick mucus formed, blocks the airways and causes difficulty in breathing and frequent lung infections.

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