There's a possible link between prostate cancer and some viruses. Is there a feature of Prostate cancer that can suggest that this cancer has a viral etiology before the virus is identified
It has been proved trhrough clinical samples of various countries that there is evidence of cause of prostate cancer by the infection of virus.polyomaviruses BKV, JCV, and SV40; human papillomaviruses (HPVs), and human cytomegalovirus (HCMV) are involved in the prostate cancer. The intronic long non coding RNA PCA3 and many are markers of prostate cancer.
Genotyping of the sample shows the link of viruses with the cancers. Till now more than 100 pappiloma viruses are linked with the etiology of the prostate cancer but no significant proof is there to show direct colink with the cancer.
BUt, RNASEL (formerly HPC1) mutation cause the risk of prostate cancer that is quite unrelated to the virus infection. However this gene is later discoverd in Virus too. This information shows that the prostate cancer was discovered before the discovery of prostate cancer and virus infection.
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