Question

Which of the following are true regarding B cell development? i. B cell precursors rearrange VDJ...

Which of the following are true regarding B cell development?
i. B cell precursors rearrange VDJ genes in the bone marrow
ii. Immature B cells only have one chance to rearrange VDJ genes to pass negative selection
iii. Immature B cells interact with follicular dendritic cells in the bone marrow to induce maturation
iv. Mature B cells circulate between lymph, blood, and secondary lymphoid tissues to find their specified antigen

i, iv

i, ii, iii, iv

i, iii

i, ii, iv

Homework Answers

Answer #1

All the options are correct with respect to the B cell development

This diagram depicts the stages of B cell development

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Which of the following statements about induction or maintenance of T cell tolerance is NOT true?...
Which of the following statements about induction or maintenance of T cell tolerance is NOT true? a. Peripheral T cell tolerance to an antigen may be induced by persistent and repeated stimulation of lymphocytes by that antigen in tissues. b. Peripheral T cell tolerance results when T cells recognize antigen in the setting of an innate immune response to the antigen. c. Peripheral T cell tolerance to some antigens is induced when mature T cells recognize antigen and bind B7-1...
1. Multiple choice: Self-reactive B cells can be eliminated from the repertoire at several stages of...
1. Multiple choice: Self-reactive B cells can be eliminated from the repertoire at several stages of B cell maturation, including immature B cells that have already emigrated from the bone marrow into the circulation. This latter stage of tolerance induction is critical because: A. Not all self-antigens are expressed or present in the bone marrow during B cell development. B. Immature circulating B cells are more sensitive to antigen stimulation than the developing B cells in the bone marrow. C....
11.) Antibodies can bind to and coat bacteria which stimulates cellular phagocytosis by ___________. This process...
11.) Antibodies can bind to and coat bacteria which stimulates cellular phagocytosis by ___________. This process is called _____________. neutrophils and macrophages; cytolysis mast cells and basophils; cytolysis dendritic cells and eosinophils; opsonization dendritic cells and macrophages; opsonization basophils and macrophages; opsonization 12.) One characteristic of the adaptive immune response is specificity. This means that the immune response is identical no matter how many times the antigen is presented . the immune response is carried on by a specific group...
1.  Which of the following is a potential route of immunization?              a.  intravenous b.  subcutaneous        &nbsp
1.  Which of the following is a potential route of immunization?              a.  intravenous b.  subcutaneous               c.  intramuscular                         d.  intradermal                         e.  all of the above 2.  Class II MHC molecules are associated with:                         a.  all T cells                         b.  B cells                         c.  CD4 cells                         d.  CD8 cells                         e.  T regulatory cells 3.  The two alpha helices that act as an Antigen Binding site for processed protein  fragments is called: Histocompatibility complex Invariant chain Chaperone protein Peptide binding groove Cytosol 4. Hypersensitivity Type I, II and III are antibody mediated and are categorized by the different antigens...
How did inoculation with cowpox generate immunological memory and provide protection against smallpox? Did cross-reactivity play...
How did inoculation with cowpox generate immunological memory and provide protection against smallpox? Did cross-reactivity play a role? How did Pasteur’s work with attenuated (weakened) bacteria further our understanding of the role vaccination can play? What are the three characteristics that define an adaptive immune response? Briefly define each of the characteristics. Define primary versus secondary immune response. What’s the difference between totipotent, pluripotent, multipotent and oligopotent when evaluating cell differentiation capacity? What is hematopoiesis? What cell types are derived...
Which of the following hypersensitivities is matched correctly with its cause? a.    Type I hypersensitivity: IgE-mediated...
Which of the following hypersensitivities is matched correctly with its cause? a.    Type I hypersensitivity: IgE-mediated b.    Type II hypersensitivity: Effector T cells c.    Type III hypersensitivity: Immune complex deposition in tissues d.    Type IV hypersensitivity: IgE attached to mast cells e. Type IV hypersensitivity: IgG-mediated
Place the following statements that describe the 5 steps in an adaptive immune response in the...
Place the following statements that describe the 5 steps in an adaptive immune response in the order in which they occur. -Long lived-immune cells allow the second response to a given microbe to be stronger and faster than the first response -Adaptive immune cells are born in the bone marrow, then mature in either the bone marrow or the thymus -Adaptive immune cells use specific receptor proteins to bind to antigens very specifically -Intracellular signaling pathways are initiated, causing the...
Which of the following statements are true regarding UNSYSTEMATIC RISK? I. Unsystematic risk can be effectively...
Which of the following statements are true regarding UNSYSTEMATIC RISK? I. Unsystematic risk can be effectively eliminated through portfolio diversification. II. Unsystematic is compensated for by a risk premium. III. Unsystematic risk is measured by beta. IV. As rational investors hold well-diversified portfolios, the market will not pay a risk premium for holding unsystematic risk. A. I and IV only B. II only C. II and III only. D. I, III, and IV only. E. III and IV only. You...
i. Hemoglobin is a protein that carries oxygen. Please tell which of the following statements are...
i. Hemoglobin is a protein that carries oxygen. Please tell which of the following statements are correct. a. when PO2 is low (30-40mmhg) the hemoglobin protein saturation increases b. when PO2 is high (75-100mmhg) the hemoglobin protein is almost entirely saturated c. when PO2 is high (75-100mmhg) the hemoglobin saturation is low d. all of the above ii. Blood circulation to lungs includes two systems. Identify which statement most accurately describes the blood circulation present int he lungs. a. The...