Question

How do tumor promoters contribute to the development of cancer? How is this process distinct from the role of carcinogens in the initiation of cancer?

Answer 1

tumor promotors help in spread of tumor and its further growth & proliferation. they are chemical compounds or biomolecules which help in promoting tumor formation they theirself do not play role in carcinogenesis initiation. they promote tumor formation by suppressing functions of tumor suppressors such as p53, BRCA1/2 genes andproteins. they also alter genetic information and promote cell growth of tumor. the tumor promotion has nothing to do with tumor initiation but it play a major role in growth of tumours.