Question

Convert 14C-labeled Pyruvate into 14C-labeled Acetyl-CoA. Show the product of each of the three steps catalyzed...

Convert 14C-labeled Pyruvate into 14C-labeled Acetyl-CoA. Show the product of each of the three steps catalyzed by the pyruvate dehydrogenase complex.

Homework Answers

Answer #1

Ans: The reaction is drawn on the paper enclosed below:

As it is not specified in the question that which carbon atom in pyruvate is radioactive so i'm taking all the 3 carbons as radioactive one:

Sorry for the cuts and bad handwriting.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Acetyl coA is made from pyruvate in the ["mitochondrial matrix" or "cytoplasm"] by ["pyruvate dehydrogenase" or...
Acetyl coA is made from pyruvate in the ["mitochondrial matrix" or "cytoplasm"] by ["pyruvate dehydrogenase" or "succinate dehydrogenase"] complex. In this process, the acetyl group is moved between enzymes within the complex by the ["lipoamide" or "TPP"]. The ["dihydrolipoyl transacetylase" or "pyruvate dehydrogenase component"] is the enzyme in which acetyl coA is actually formed. The ["FADH2" or "lipoamide"] in the dihydrolipoyl dehydrogenase donates two electrons to NADH, which then goes on to the electron transport chain.
Draw the structure of a stearic acid molecule (C18:0). If it was synthesized with 14C acetyl-CoA...
Draw the structure of a stearic acid molecule (C18:0). If it was synthesized with 14C acetyl-CoA labeled only on the carboxyl carbon, clearly show where all of the labels are found in the final molecule.
Order the following steps in the pyruvate dehydrogenase reaction. The answer is scored as ALL OR...
Order the following steps in the pyruvate dehydrogenase reaction. The answer is scored as ALL OR NOTHING, so all steps must be in the correct order for credit. Question 5 options: a) Pyruvate and thiamine pyrophosphate react form hydroxyethyl-TPP. CO2 is released. b) The reduced coenzyme bound to PDH is reoxidized using electrons from FAD. c) An acetyl group is added to a coenzyme bound to PDH, forming acetyl-dihydrolipoamide. d) The acetyl group is transferred to CoA, forming acetyl-CoA. e)...
Describe how the product from glycolysis is converted to the activated metabolite acetyl-CoA. It is sufficient...
Describe how the product from glycolysis is converted to the activated metabolite acetyl-CoA. It is sufficient to state the total reaction. Where in the eukaryotic cells does this transformation take place? What is meant by acetyl-CoA being an activated metabolite? What are the enzyme complex that catalyzes conversion to acetyl-CoA, and how many enzymes and coenzymes does this complex consist of?
1. What is the number of ATP obtained from one acetyl CoA in the citric acid...
1. What is the number of ATP obtained from one acetyl CoA in the citric acid cycle? 2. For each molecule, identify the location where enzymes are available to metabolize them. Location options are Extracellular Space, Mitochondria, or Cytosol. ..... Polysaccharides Pyruvate Glucose Galactose Acetyl CoA Fructose 3. Put the enzymes (below) of glycolysis in the order in which they appear in the glycolytic pathway, from first to last. Fructose-1,6-biphosphate aldolase phosphoglucoisomerase hexokinase phosphofructokinase triosephosphate isomerase 4.   Put the enzymes...
4. a. Pyruvate dehydrogenase (the complex) catalyzes which reaction? Show the substrates and products. b.Name the...
4. a. Pyruvate dehydrogenase (the complex) catalyzes which reaction? Show the substrates and products. b.Name the coenzymes required and explain the function of each one. c.List one positive and one negative allosteric modulator. d.Where in the cell does this reaction take place
Propionyl-CoA is found within mammalian cells, arising from at least three sources. What are the sources?...
Propionyl-CoA is found within mammalian cells, arising from at least three sources. What are the sources? Elaborate. In 3 enzyme catalyzed steps, the propionyl-CoA is ultimately converted to succinyl-CoA, a process that requires bicarbonate. Imagine that you have an in vitro set-up of 13C-labelled propionyl-CoA (label on the middle C of propionyl), unlabelled bicarbonate, and the enzymes. By showing the three relevant equations, indicate the location of the 13C-label in each step and in the product succinyl-CoA.   It is NOT...
Add decimal numbers using binary additions for 170 and 493. Steps: Convert each number to binary...
Add decimal numbers using binary additions for 170 and 493. Steps: Convert each number to binary first. Then add the two binary numbers using binary addition. Make sure to keep track of the carry bit and show the carry for each step even when it is zero. Please show all work.
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...
Please show your steps for each part of the problem, and if a calculator was used,...
Please show your steps for each part of the problem, and if a calculator was used, list the button combination pressed in order to arrive at your answer! a. Jack and Jill are twins and at 20 years of age they both opened separate investment accounts with an on online broker. Jack started investing $50 a month starting from today. Jill will save $55 a month starting at the end of the month. if this investment account gives them 8%...