Question 11 [20 marks / 20 minutes]
This question is about mechanisms of gene regulation in
eukaryotes.
a) In Drosophila melanogaster, Sex-lethal (Sxl) controls somatic
sexual development.
i. Describe the regulatory mechanism that leads to the presence of
Sxl protein only in female early embryos. [4 marks]
ii. Explain how this difference is maintained later in the life
cycle [6 marks]
b) List two RNA modifications present in eukaryotes. Describe in
detail the function of one of these RNA modifications in a living
cell. [6 marks]
c) Describe the function of two different DNA and/or histone
modifications present in eukaryotes. [4 marks]
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