Question

Designer Receptors Exclusively Activated by Designer Drugs (DREADD) are:

Select one:

a. activated by clozapine-N-oxide (CNO) administration

b. inhibited by orange light

c. none of these choices

d. activated by blue light

e. inhibited by hM3Dq receptor agonists

Answer 1

The answer is the option a - activated by Clozapine N Oxide (CNO) administration

Designer Receptors Exclusively Activated by Designer Drugs (DREADD) are genetically engineered receptors based on chemogenetics and helps in controlling G protein signaling. DREADDs are introduced into the cells for controlling the activities of the cell. These genetically engineered receptors introduced in the cells are inactive until the administration of  Clozapine N Oxide (CNO). Clozapine N Oxide (CNO) is the drug that activates DREADDs

Therefore the answer is option a