Question

Dogs are getting cancer because of the SRC retrovirus. The viral transforming gene, v-src, is missing the ligand-binding domain compared to the c-src gene. Is a mAb therapy strategy likely to be useful in treating the virally-caused cancer? Briefly explain.

Answer 1

SRC Retrovirus is causing cancer in dogs because the retrovirus is oncogenic in nature. This occurring takes place as the c src is converted to v src. It is to be taken into consideration that c src is a proto oncogene but v src is an oncogene. The v src misses the ligand binding domain which is present in the original c src. However, here we are to discuss about monoclonal antibodies and how it can be used as a therapy in treating virally induced cancer. Monoclonal antibody therapy is a very good option of immunotherapy as it aids the immune system to take over the cancerous cells by targeting them and killing them.They are manufactured to target only specific antigen which are present on the cancer causing viruses. They induce a long term antiviral response in the body and therefore can regulate such cancers and prevent them from occurring.