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Why it is unsafe to drink caffeinated drinks before the S phase? short and precise answer...

Why it is unsafe to drink caffeinated drinks before the S phase?

short and precise answer please :) !

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Answer #1

Caffeine (1,3,7-trimethylxanthine ) is used as a neuroactive stimulant. Excessive intake before S phase (G1) may pause/suppress cell proliferation and cell function ,it can cause cell arrest, apoptosis & perturb key regulatory proteins(like p53: tumor suppressor protein ).

p53 mediates cell arrest and apoptosis. Cells expressing wildtype arrest in G1 phase and cells which cannot express p53 express a mutant p53 so arrest in G2 phase.

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