What is the difference between convergent versus divergent signaling pathways ?
Convergent signals:
The signals from a variety of unrelated receptors converge to activate a common effector after binding to their individual ligands. Ex: Ras Raf
These signals are usually from receptors.
Ex: G-protein coupled receptors, Receptors of tyrosine kinase and Integrins.....etc
Divergent signals:
Signals from same ligand diverge to activate a variety of different effectors leading to diverse cellular responses.
These effects are usually ligand based. Ex : EGF Ligand, Insulin Ligand
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