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Describe the role of acetyl-CoA carboxylase (ACC) in regulation of β-oxidation.

Describe the role of acetyl-CoA carboxylase (ACC) in regulation of β-oxidation.

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Answer #1

Beta oxidation occur when a fatty acid is broken down into the units of acetyl CoA. It occur at the beta carbon and take place in mitochondria.
Acetyl CoA carboxylase is the main enzyme which is involved in Beta oxidation of fatty acid. Mainly, the enzyme functions by catalysing the reaction of acetyl CoA carboxylation in order to produce malonyl CoA. And this is achieved by two activities, first carboxyltransferase and second biotin carboxylase.
Malonyl CoA will be used up by the enzyme fatty acid synthase that will be required to catalyse the synthesis of fatty acid.
Function of Acetyl CoA carboxylase:
This enzyme is mainly involved in regulating the fatty acid metabolism. Acetyl CoA carboxylase when active will yield the product named as malonyl CoA.

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