Question

How is the mouse Sey gene able to rescue the function (and vision) of a fly with a deleted ey gene when only 29% of the amino acids between the mouse Sey and the fly ey gene are identical?

What is the difference between a mutation and a polymorphism?

Humans and chimpanzees have almost identical genes, but there is evidence that ________ occurred millions of years ago. How many occurrences of ________ have led to the differences between the two species today?

How does gene amplification lead to genomic effects including cancer when no mutations occur in the protein-coding region of an amplified gene?

Explain why a virus would “want” to cause cancer in its host.

How does percent identity differ from percent similarity?

Would the human trypsin gene and the shrimp trypsin gene be considered orthologs or paralogs?

Would the His4 protein and the HisF protein of Thermotoga maritima be considered orthologs or paralogs?

Define synteny in your own words.

Answer 1

As, the mouse sey gene and fly ey gene are encoded by homologous gene . This means both the gene is under similar genetic control. Hence, mouse sey gene is able to rescue the function of the fly ey gene.

Mutation is the change in the nucleotide sequences of an organism. Mutation are generally lethal and not common in population whereas polymorphism means mutation which is common in population and is not lethal.

Percent identity means the number of nucleotide base and amino acids are exactly similar, whereas similarity means the number of nucleotide and amino acid which are somewhat similar. For example, A base is identical to A in other sequence whereas A is similar to G because both are purine.

Synteny is used to describe the situation where two genes are located on the same chromosomes within individual or in species.