Question

Enzymes prefer to bind to the transition state which is the species with the highest affinity....

Enzymes prefer to bind to the transition state which is the species with the highest affinity.

True or false?

Homework Answers

Answer #1

The enzymes have a greater affinity for the transition state. The activation energy is lowered when the enzyme binds the transition state. The components of the protein interact with the unstable transition state.

The active site of the enzyme binds to the transition state better than it binds with the substrate and the enzyme's catalytic activity is greater when it binds more tightly to the transition state than the substrate.

Hence, the statement is TRUE.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Which of the following is NOT a mechanism employed by enzymes to lower the energy of...
Which of the following is NOT a mechanism employed by enzymes to lower the energy of the transition state? High substrate binding affinity ? General acid/base catalysis? Metal ion catalysis ? Covalent catalysis ? Proximity and orientation effects?
Which statement is NOT true about transition state? a. It has higher free energy than the...
Which statement is NOT true about transition state? a. It has higher free energy than the substrate b. It fits enzyme active site better (with higher affinity) than the substrate c. It helps stabilize tertiary structure of an enzyme d. It exists for a very short time during the reaction
1. true or false: substrates frequently bind to the active site of enzymes using a covalent...
1. true or false: substrates frequently bind to the active site of enzymes using a covalent bond 2. true or false: a competitive inhibitor of an enzyme-catalyzed reaction maintains the same Vmax of the reaction and increase the KM 3. when dividing cells, the physical separation of chromosomes during the mitotic phase depends on what molecular complexes? a. microtubules b. myosin and actin filaments c. myosin d. kinesin e. microtubules motors and microtubule
1. Which of the following is not true about receptors? A. They must have affinity for...
1. Which of the following is not true about receptors? A. They must have affinity for a substrate to bind. B. They are made of proteins, carbohydrates or lipids. C. They can become saturated. D. They are specific E None of the choices are not true. All of these choices are true about receptors
16. Which of the following is NOT true about enzymes? A) Some enzymes require cofactors. B)...
16. Which of the following is NOT true about enzymes? A) Some enzymes require cofactors. B) Enzyme inhibitors may interact either reversibly or irreversibly with an enzyme to alter its Km and /or Vmax values. C) Transition state stabilization can significantly increase the activation energy for a reaction. D) Enzymes typically act under milder conditions of temperature and pH than (nonenzyme) chemical catalysts. E) Zymogens are a form of inactive precursors of enzyme.
Which of the following are not true of enzymes? Select one: a. The catalytic activity of...
Which of the following are not true of enzymes? Select one: a. The catalytic activity of enzymes is often regulated. b. Enzymes have great catalytic power. c. Enzymes bind substrates with high specificity. d. Enzymes are proteins/RNA. e. Enzymes use hydrophobic interactions exclusively in binding substrates.
1)To lower the energy barrier in a reaction, enzymes change the path of the reaction between...
1)To lower the energy barrier in a reaction, enzymes change the path of the reaction between the reactants and products by doing what? A. Destabilizing the transition state by increasing the free energy to be used and lowering the activation energy B. Releasing carbonic acid into the environment to stabilize the transition state and lowering the activation energy C. Reduce the activation energy by stabilizing the transition state and decreasing its free energy D.Supply heat to stabilize the reactants and...
Hemoglobin (Hb) can be viewed as having two quaternary states, a low oxygen affinity state (T),...
Hemoglobin (Hb) can be viewed as having two quaternary states, a low oxygen affinity state (T), and a high oxygen affinity state (R). Which of the following statements about the binding of O2 by Hb are true? 1) Upon binding a molecule of oxygen, Hb undergoes a conformational change that makes the binding of subsequent O2 molecules easier. 2) The conformational change induced in Hb upon binding oxygen is the result of a small movement (0.2 Å) of the iron...
please answer all 7-11 7. Which is not true for enzymes: A. The active site is...
please answer all 7-11 7. Which is not true for enzymes: A. The active site is a three dimensional crevice in the protein. B. Enzymes produce a more negative value for ΔG. C. Most substrates bind enzymes by forming multiple weak interactions. D. The active site takes up only a small part of the enzyme’s volume. 8. What are the two types of cofactors associated with enzymes? (6 points) 9. Explain the function of the following substances in solid phase...
Which of the following statement is not true. a. an endothermic reaction has an early transition...
Which of the following statement is not true. a. an endothermic reaction has an early transition state. b. the transition state of an exothermic reaction resembles reactants. c. the activation energy of the forward reaction of an exothermic reaction is less than the activation energy of its reverse reaction. d. an endothermic reaction requires energy to proceed in the forward direction.