Enzymes prefer to bind to the transition state which is the species with the highest affinity.
True or false?
The enzymes have a greater affinity for the transition state. The activation energy is lowered when the enzyme binds the transition state. The components of the protein interact with the unstable transition state.
The active site of the enzyme binds to the transition state better than it binds with the substrate and the enzyme's catalytic activity is greater when it binds more tightly to the transition state than the substrate.
Hence, the statement is TRUE.
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