Electron Transport and Oxidative Phosphorylation
1. What is the source of most of the energy utilized in ATP synthesis? Is this the same source for complex II?
2. What is the role of coenzyme Q in electron transport in Complex I? Complex II?
3. Is complex II a mobile redox center or stationary must electrons pass through it to Go to complex III?
Explain the following statement in your own words:
Since the free energy of oxidation of fully reduced coenzyme Q by cytochrome c is captured by the generation of a proton gradient across the inner mitochondrial membrane, the Q cycle doubles the thermodynamic efficiency of this process.
Q1:- Explanation:-
The source of most of energy for ATP synthesis in ETC ( electron transport chain) during respiration is NADH2 that get oxidised to give protons and electrons these protons move into inermembrane space of mitochondria and generate proton motive force (PMF) that is responsible for ATP synthesis via ATP synthase. In complex II the FADH2 acts as energy source not NADH2. This complex II is called Succinate dehydrogenase that converts succinate into fumarate.
Q2:- Cornzyme Q also called ubiquinone that is lipid aoluble mobile carrier that takes electrons from complex I and II and gets reduced to ubiquinol.
Q3:- Complex II also called succinate dehydrogenase that takes electrons from FADH2 to complex III via UQ and thus is stationary.
Statement:- The Q cycle increases the proton gradient across intermenbrane space . Thus Quinone cycle involves cytochromes etc.
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