Question

A major difficulty in studying the properties of pancreatic serine proteases is that these enzymes are...

A major difficulty in studying the properties of pancreatic serine proteases is that these enzymes are self-digesting. Provide a detailed rationale for the observation that the problem is less severe for solutions of chymotrypsin than it is for solutions of trypsin.

Homework Answers

Answer #1

Both the enzyme, whether it is trypsin and chymotrypsin, are proteolytic enzymes. Both the enzymes cut the proteins from c-terminal. These enzymes are also considered as proteinases which splits the large proteins and also helps in cleaving the internal peptide bonds of shorter peptides. But the trypsin digests the basic amino acid such as Arginine & Lysine while chymotrypsin digests the aromatic amino acid and along with this various ester and amide derivatives of aromatic amino acid are also digested by chymotrypsin. Chymotrypsin is also more active enzyme comparative to trypsin.

If this helps you then please Rate it. Thanks and regards

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
In studying the mechanism of serine proteases, scientists A and B introduce mutations into the enzymes...
In studying the mechanism of serine proteases, scientists A and B introduce mutations into the enzymes and monitor the resulting enzyme activity. One mutation changes the serine of the catalytic triad to cysteine. (10 points) a. Scientist A thinks this mutation will increase the activity of the enzyme. Briefly explain the reasoning behind scientist A’s hypothesis. b. Scientist B thinks this mutation will reduce the activity of the enzyme. Briefly explain the reasoning behind scientist B’s hypothesis.
what is the issue in Emaar case study ? (10marks) Emaar Properties specializes in creating value-added,...
what is the issue in Emaar case study ? (10marks) Emaar Properties specializes in creating value-added, master-planned communities that meet the full spectrum of lifestyle needs. Highlights include Downtown Dubai, the 500-acre mega-project including Burj Khalifa – the world’s tallest building, and The Dubai Mall—the world’s largest shopping and entertainment destination. Emaar is extending its expertise in developing master-planned communities internationally, and has established operations in the United Arab Emirates, Saudi Arabia, Syria, Jordan, Lebanon, Egypt, Morocco, India, Pakistan, Turkey,...
please choose and write true answer only and quickly?? The key elements of domestic violence are...
please choose and write true answer only and quickly?? The key elements of domestic violence are all of the following except:       Apology.    Intimidation. Physical injury.     Humiliation. ********* Nurse Angela is working in the emergency department of Medical Center. She is conducting an interview with a victim of spousal abuse. Which step should the nurse take first? Establish a rapport with the victim and the abuser. Request the presence of a security guard Ensure privacy for interviewing...
Item 1 In the case below, the original source material is given along with a sample...
Item 1 In the case below, the original source material is given along with a sample of student work. Determine the type of plagiarism by clicking the appropriate radio button. Original Source Material Student Version There is a desperate need for theorists and researchers to generate and refine a new breed of learning-focused instructional design theoriesthat help educators and trainers to meet those needs, (i.e., that focus on learning and that foster development of initiative, teamwork, thinking skills, and diversity)....
What tools could AA leaders have used to increase their awareness of internal and external issues?...
What tools could AA leaders have used to increase their awareness of internal and external issues? ???ALASKA AIRLINES: NAVIGATING CHANGE In the autumn of 2007, Alaska Airlines executives adjourned at the end of a long and stressful day in the midst of a multi-day strategic planning session. Most headed outside to relax, unwind and enjoy a bonfire on the shore of Semiahmoo Spit, outside the meeting venue in Blaine, a seaport town in northwest Washington state. Meanwhile, several members of...