Question

1.When phage infect a bacterial cell, they typically have a temporal program of gene expression, i.e., they express particular genes at particular times. What are two regulatory mechanisms phage use to control their gene expression?

1b.What is alternative splicing? Draw an example of two alternative spliced products

Answer 1

The phages encode a specialized class of protein factors ( Gp39 protein, ? phage N protein) to regulate the host RNAP specificity or encode RNAP to initiate its own gene transcription.

Alternative splicing- It is a mechanism by which genes are regulated by gene expression that results in a single gene coding for multiple proteins. Before mRNA is translated it must be first modified and this modification is done with alternative splicing where exons or portions of exons are joined or excluded in multiple ways,