Question

Which statement is Not true for glycolysis under anaerobic conditions in a msucle:

a. Fructose - 1,6-biphosphate is a substrate in the glycolysis process

b. It results to compete glucose oxidation to CO2

c. It results in net ATP production

d. It results in NADH production

e. Its speed decreases as ATP concentration increases

Answer 1

In the presence of limited amounts of oxygen, the glucose is transformed to lactate in anaerobic glycolysis.

In the absence of sufficient oxygen in the muscle cells for further NADH produced and oxidation of pyruvate in glycolysis, the reduction of pyruvate to lactate results in the regeneration of NAD+ from NADH.

The enzyme Fructose 1,6-bisphosphatase converts the substrate fructose-1,6-bisphosphate to fructose-6-phosphate.

This process results in net synthesis of ATP and NADH production and its rate slows down when ratio is high.

Hence, the option (b) is correct.