Question

What is recombination and how is it used to repair DNA damage?

What is recombination and how is it used to repair DNA damage?

Homework Answers

Answer #1

During the meiosis process of eukaryotic cells chromosomal crossing over is taken placed and the product generated from meiosis is called as a recombinant. In the crossing over homologous chromosomes can pairs with each other and transfer the genetic information from each other. In independent assortment a novel set of genetic information that can be passed on from the parents to the offspring. So the output cell of meiosis has the same genetic constitution of one of the input cells in the recombination.

If the DNA repairs via homologous recombination then both the damaged part is replaced by original one so the length is not reduced and it revert back to its original form.? The recombination mechanisms performed by Rec A,RecB RecC proteins. So this recombination process can used to repair DNA damage.

If you are satisfied with my answer please rate it.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Which process is used to replicate DNA that contains distortions due to unrepaired DNA damage? A.  Nonhomologous...
Which process is used to replicate DNA that contains distortions due to unrepaired DNA damage? A.  Nonhomologous end joining B.  Homologous recombination repair C.  Nucleotide excision repair D.  Translesion synthesis D.
2. Haploid yeast cells that preferentially repair double-strand breaks by homologous recombination are especially sensitive to...
2. Haploid yeast cells that preferentially repair double-strand breaks by homologous recombination are especially sensitive to agents that cause double-strand breaks in DNA. If the breaks occur in the G1 phase of the cell cycle (before DNA replication), most yeast cells die; however, if the breaks occur in the G2 phase (after DNA replication), a much higher fraction of cells survive. (a) What are the key proteins required for homologous recombination in yeast (a eukaryote)? (b) Yeast can also carry...
Following homologous recombination, the mismatch repair system is induced. Briefly explain the specific reason(s) that this...
Following homologous recombination, the mismatch repair system is induced. Briefly explain the specific reason(s) that this system is induced to repair DNA following homologous recombination.
A cell fails to repair DNA damage after synthesis. Will the G2/M cyclin be synthesized? Explain...
A cell fails to repair DNA damage after synthesis. Will the G2/M cyclin be synthesized? Explain your reasoning.
What two DNA repair systems are used by the immune system, and why?
What two DNA repair systems are used by the immune system, and why?
For DNA damage that cannot be repaired by direct reversal, such as deamination, oxidation and alkylation,...
For DNA damage that cannot be repaired by direct reversal, such as deamination, oxidation and alkylation, what is the main repair pathway? How conserved is this pathway in various organisms?
Please simply describe recombination repair.
Please simply describe recombination repair.
DNA Repair 1. Most mutations are deleterious. However, in the right environment, mutations can be advantageous....
DNA Repair 1. Most mutations are deleterious. However, in the right environment, mutations can be advantageous. Describe an example where this is the case. 2. Define mutation. 3. What are the three types of mutations that can result from modifications to the nucleotides of the DNA? 4. How are mutated nucleotides repaired? 5. Describe the process of DNA mismatch repair. 6. Why use the old strand of DNA to correct errors during DNA mismatch repair as opposed to the new...
Pick the statement about DNA repair that is true. Base excision repair removes bulky DNA lesions...
Pick the statement about DNA repair that is true. Base excision repair removes bulky DNA lesions like thymidine dimers. Nucleotide excision repair is used immediately after replication to correct errors that escape proofreading. Direct repair directly changes modified bases back to their original structure. Mismatch repair reduces the fidelity of DNA polymerase. SOS repair uses DNA glycosylases to recognize and remove a specific type of modified base.
In theory, a genome editing method like CRISPR could be paired with repair by homologous recombination...
In theory, a genome editing method like CRISPR could be paired with repair by homologous recombination to cure DMD. However, repair by homologous recombination is rather inefficient. An alternative method is to use genome editing, paired with non-homologous end joining (NHEJ). Briefly explain how this strategy would work for DMD, and if it were 100% efficient, what you would expect it to do patient symptoms.