Question

You have determined the genetic linkage of seven point mutants (r1, r2, r3, r4, r5, r6,...

You have determined the genetic linkage of seven point mutants (r1, r2, r3, r4, r5, r6, and r7). Luckily for you, the map order of the point mutants corresponds to their name, i.e., point mutant r2 is located between point mutants r1 and r3, etc.

You wish to locate the deletion mutants r11, r12, and r13 onto this linkage map. To this end, you conduct pair-wise crosses between the deletion mutants and the point mutants to determine if r+ recombinants can be obtained. Your results are shown in this table, where a "+" indicates the presence of r+ recombinants.

Point mutants
Deletion mutants r1 r2 r3 r4 r5 r6 r7
r11 + + + + 0 0 0
r12 + + 0 0 0 + +
r13 + + + + + 0 +

Indicate all the point mutations that are not within the boundaries of the deletion present in mutant r11.

Select all that apply.

Select all that apply.

r1
r2
r3
r4
r5
r6
r7

Homework Answers

Answer #1

When two mutants are crossed and the resultant F1 progeny shows WT phenotype, it means that both the mutations are located in different genes. i.e. they are non-allelic.

When two mutants are crossed and the resultant F1 progeny shows mutant phenotype, it means that both the mutations are located in the same gene. i.e. they are allelic to each other.

'+' means WT phenotype

'-' means mutant phenotype

From the given table,

r11 is not allelic to r1, r2, r3, and r4 i.e. r1, r2, r3, and r4 are not located within the r11.

r11 is allelic to r5, r6, and r7 i.e. r5, r6, and r7 are located within the r11.

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