Question

Put these steps in neuromuscular junction synaptic transmission and excitation-contraction coupling in chronological order.

(Type the letters in the appropriate order with no spaces between them).

A. Ryanodine receptors open
B. Voltage-gated Na+ channels open in the muscle cell membrane near the neuromuscular junction
C. Tropomyosin rotates into the groove of the thin filament (out of the way of the myosin binding site)
D. Depolarization of motoneuron axon terminal
E. Ca2+ dissociates from troponin
F. [Ca2+] rises in the muscle cell cytoplasm
G. An EPSP occurs in the muscle cell
H. Myosin heads go through the cross-bridge cycle and hydrolyze ATP
I. An action potential is conducted along the T-tubule
J. Acetylcholine receptors open and conduct Na+ ions
K. Ca2+ binds to Troponin
L. Vesicles containing acetylcholine fuse with nerve cell membrane

Answer 1

Vesicles containing acetylcholine fuse with nerve cell membrane
Depolarization of motoneuron axon terminal
Acetylcholine receptors open and conduct Na+ ions
Voltage-gated Na+ channels open in the muscle cell membrane near the neuromuscular junction
An EPSP occurs in the muscle cell
An action potential is conducted along the T-tubule
Ryanodine receptors open
[Ca2+] rises in the muscle cell cytoplasm
Ca2+ binds to Troponin
Tropomyosin rotates into the groove of the thin filament (out of the way of the myosin binding site)
Myosin heads go through the cross-bridge cycle and hydrolyze ATP
Ca2+ dissociates from troponin