Question

Please answer the following questions. Your reply to each of the questions should be 50 -100 words in length. It must be in your own words and remember to cite your sources.

1)    List the different T cell subsets, their functions and their unique receptors, especially T cell receptor.

2)    Discuss any TWO cytokines from the list below as regards, the type, sources and function. (e.g. IL1 and IL 2)

a)    Interleukins- IL 1, IL 2, IL 4, IL 6, IL 10 & IL 14

b)    Tumor necrosis factors: TNF- Alpha & Beta

c)    Interferons – Alpha, Beta and Gamma

Answer 1

1.Mainly different types of T cells subsets are: CD4 and CD8 cells

CD4:they play important role in immune system mainly in adaptive immune system.

CD8:they play main function in killing cancer cells,damaged cells,infected cells

T cell receptors is molecule found on surface of T cells and responsible for identifying fragments of antigen as peptide bound to major histocompability molecules.

2.

IL1:

type:cytokine group

source:activared by microphages

function-it activates monocytes,macrophages,osteoclast etc

IL2.

type:cytokine group

source:activated CD4 T cells produced IL2

function:main function is to promote development of T regulatory cells.