Question

1.a) In the genetic code, the codon GAU encodes _________.

Select one:

a. Aspartic acid.

b. Asparagine.

c. Terminator (stop codon).

d. Serine.

e. Methionine (initiator codon).

b) An individual with the genetic condition cystic fibrosis has a CFTR protein with the amino acid histidine at position 482. The normal CFTR protein has arginine. at position 482. No other changes are observed in the protein. This is change is likely the result of a _________ mutation.

Select one:

a. Frameshift.

b. Missense.

c. Nonsense.

d. Silent.

c) You are scanning a strand of DNA looking for promoter regions. What might you look for?

Select one:

a. The sequence Thymine-Adenine-Thymine-Adenine

b. A polyadenylation signal sequence

c. The sequence for RNA polymerase

d. The sequence for small nuclear ribonucleoproteins

e. You should search for all of the above.

Answer 1

1. Aspartic acid

GAU codon codes for aspartic acid. You need to see genetic code for this.

A codon is a set of three nucleotides present on mRNA and codes for one amino acid.

2. Missense

Missense mutation - change in nucleotide also changes the amino acid

Nonsense mutation - change in nucleotide results in the formation of stop codon thereby formation of truncated peptide

Silent mutation - change in nucleotide but no change in amino acid

3. A

Promoter is a sequence on DNA where RNA polymerase binds to initiate transcription of downstream genes.

It is rich in GC or AT.

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