Question

Jessica a 62 year old female, comes to the clinic complaining of fatigue and persistent shortness of breath, which becomes worse during exercise. She has a history of respiratory infections and a chronic cough that is worse in the morning. She worked for 20 years in an automobile manufacturing plant and was laid off 5 years ago. Jessica had smoked cigarettes since she was a teenager and currently smoking one pack per day.

A) what would you expect her Arterial Blood Gas (ABG) test results to reveal (i.e serum pH, PCO2, PO2, and serum HCO3)?

B) In the case of an exacerbation of her condition would proving her with pure oxygen be recommenced? Explain how such a pure oxygen treatment would affect her ABG value.

C)Certain long acting Beta-adrenergic agonists used to treat COPD tigger bronchodialtion by inhibiting myosin kinase and blocking membrane Ca2+ channels in bronchiolar smooth muscle cells. Explain how each of these actions will promote relaxations in smooth muscle cells

Answer 1