Question

In a hypersensitivity reaction such as a drug allergy, which cells release histamine that results in...

In a hypersensitivity reaction such as a drug allergy, which cells release histamine that results in itching, congestion, drop in blood pressure?

T cells

B cells

Mast cells

both (a) and (b)
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Answer #1

Anwer is Mast cells.

In a hypersensitivity reaction such as drug delivery, mast cells releases the histamine that results in Itching, congestion, drop in blood pressure.

When mast cells are activated by an allergen will binds to serum IgE attached to their Functional Expression of the High Affinity Receptor for IgE receptors, they release cytokines, eicosanoids and their secretory granules.

Mast cells are also play a vital role in immunoregulatory roles, in various immune disorders through the release of mediators such as histamine, leukotrienes, cytokines chemokines, and neutral proteases (chymase and tryptase).

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