Question

Non-competitive enzyme inhibition can be explained by which model of enzyme function

		the induced fit model
		the lock and key model
		both a and b
		neither a nor b

Answer 1

Lock and key theory .the shape of the enzyme's active is complementary to that it's substrate (2) Induced fit theory .The active site is flexibility of shape , thus ,when an appropriate substrate comes in contact with the enzyme's active site , would change to fit with the substrate .There are 2types of inhibitors reversible and irreversible. Reversible inhibitors are un competitive and noncompetitive inhibitors Uncompetitive inhibits only binds to enzyme substrate complex .Non competitive inhibitors and substrate binding to enzymes .