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What are 5 strategies used by the negative sense ss RNA virus influenza A virus to...

What are 5 strategies used by the negative sense ss RNA virus influenza A virus to ensure that its genes are expressed correctly?

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Ans. The five strategies, used by the negative sense ss RNA virus influenza to ensure that its genes are expressed correctly are given below:

1. Proof-reading activity of RNA dependent RNA polymerase. It allows error free synthesis of viral genome in changing environmets.

2. Recombinational mechanisms in influenza virus. It is responsible for sequence diversity and genome repair.

3. Presence of terminal transferase enzyme and poly (A) tail repair mechanism. It is responsible for genomic stability during genome replication.

4. Cap snatching. It is process, which occurs during transcription initiation and helps in the cap formation in viral mRNA to maintain its stability.

5. Gene rearrangement, such as by alternate splicing

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