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Describe the function of a gene involved in bacterial virulence (a gene that encodes for a...

Describe the function of a gene involved in bacterial virulence (a gene that encodes for a protein/factor involved in an infection process), mention the bacteria that encodes for said gene, and the disease that the infection causes in the human host.

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Answer #1

Virulence is defined as the ability of the bacteria to cause infection in the host and evade host defence mechanisms leading to the development of disease. The functions of gene involved in bacterial virulence are listed below,

  1. colonise mucosal sites by adherence with the help of pili
  2. capsules protects them from opsonisation and phagocytosis by host cells
  3. invasion factors which help them to invade the host cell membranes
  4. exotoxin and endotoxin secretion

Adherence factors are produced by the genes present in Vibrio cholerae and E. coli. With the help of these adherence factors, Vibrio cholerae adhere to the mucosa of intestinal wall and able to cause the disease.

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