Name and draw the chemical structures of two “sulfa drugs” still currently in clinical use. Briefly explain the advantages of these compounds (based on their structures) over the original prontosil molecule.
advantages over protonsil:
Protonsil in body is broken down to sulfanilamide,it is active part.
Sulfadiazine is preferred for meningitis.
Sulpamethoxale is a bacteristatic static agent. It is widely used in combination with trimethoprim as it has lower broad spectrum activity,due to development of resistance.
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