Question

Which of the following mechanisms is NOT involved in the generation of antibody diversity? Somatic hypermutation...

Which of the following mechanisms is NOT involved in the generation of antibody diversity?

Somatic hypermutation
Recombination with excision of DNA between a V gene sequence and a J sequence
Transposition
Splicing out of RNA sequences between a J region and a C region
Non-homologous end joining and DNA repair
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Answer #1

The correct choice should be

(C) Transposition and (e) non Homologous end joining and DNA repair.

Antibody diversity is a process of generation of antibodies having different characters/ binding affinities. Different abtiboantiare required to fight against different antigens.

The following process are used in the process-

Somatic hypermutation,

Recombination with excision of DNA between a V gene sequence and a J sequence,

Splicing out of RNA sequences between a J region .

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