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One consequence of starvation is loss in muscle mass. What happens to muscle proteins? Which metabolic...

One consequence of starvation is loss in muscle mass. What happens to muscle proteins? Which metabolic pathway(s) would contribute to this physiological effect?

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Due to starvation, muscle proteins are broken down to amino acids which are fed to TCA cycle and are utilized for glucose formation to fulfil energy requirements of the body via gluconeogenesis.

Amino acids are fed to TCA cycle and glucose formation takes place by gluconeogenesis. Amino acids go to liver and are deaminated into nitrogen and carbon skeleton. The carbon skeleton of amino acid is used to make glucose and the nitrogen group is converted into urea and excreted.

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