Assume that you have discovered a new mutant phenotype in zebrafish embryos that fails to produce any head structures and is lethal by day 5 of development. Describe a way to rescue the mutant phenotype; i.e., what might you inject to test for this? List some potential genes that when mutated might produce this type of phenotype. How would you go about narrowing the list in an attempt to identify the gene responsible (i.e. what genes program cells to make anterior structures)?
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