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What happens at the molecular level in normal physiology of the kidneys?

What happens at the molecular level in normal physiology of the kidneys?

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Molecular level in normal physiology of the kidney.

Tight glucose control significantly decreases , indicating that hyperglycemia-induced metabolic alterations, including changes in energy utilization and mitochondrial dysfunction, play critical roles in disease initiation. Blood pressure control, especially with medications that inhibit the angiotensin system, is the only effective way to slow disease progression.

Inflammation, cell hypertrophy, and dedifferentiation by the activation of classic pathways of regeneration further contribute to disease progression.

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