Question

How do adenoviruses avoid the adaptive immune system?

1. They cloak themselves with a hyaluronic acid capsule.

2. They interfere with antigen presentation of MHC 1 molecules.

3. They synthesize C5a peptidase.

4. They block interferon and antiviral protein production.

5. They interfere with antigen presentation on MHC 11 molecules.

Answer 1

Adenoviruses produce proteins that destroy responses through interferons, cytotoxic CD8 cells, and apoptosis. Therefore, 2^nd and 4^th option is correct. Adenoviruses affect CD8 cells response that occurs through MHC I molecules, which occurs through preventing TAP association with tapasin. Second blocking occurs through preventing interferon signaling and antiviral protein productions.

'''''''''''''''''''''''''''''''Please rate the answer''''''''''''''''''''''''''''