Question

What type of vaccine would be MOST effective against tuberculosis, a disease that requires a strong CD4⁺ T-cell response

Inactivated

Live attenuated

Toxoid

Subunit

DNA

Which of the following is NOT a good candidate for immunodeficiency replacement therapy?

Immunoglobulin

Defective genes

Hematopoietic stem cells

All of the answers are good candidates

IFN-γ

1. Which of the following is a potential cause of chronic inflammation?

   		Tissue damage
   		Intestinal commensal microbiota components
   		All of the answers are correct
   		Obesity
   		Infectious agents

1 points   

QUESTION 4

1. Myasthenia gravis is an autoimmune disease that

   		leads to destruction of muscle cells
   		All of the answers are correct
   		is triggered by antibodies
   		None of the answers are correct
   		targets the neuromuscular junction

Answer 1

Question 1.) Answer is Live Attenuated.

BCG (Bacillus Calmaette -Guerin vaccine) is the vaccine which is given to the childrens in the left deltoid region at birth. For adults after the Tuberculin test is negative it is given. It has shown efficacy in children but the efficay in adults is questioned but it provides resistant against Tb.

Question 2.) Answer is All of the answers are good candidates.

Because all of them are used in the immunodeficiency replacement therapy. Immunoglobulin as plasma replacement, defective genes are corrected by gene therapy, stem cell culture helps in developing new cells and IFN-Y has a good activity as immune developer.

Question 3.) Answer is All the answers are correct.

A tissue damage leads to inflammation as red flars are seen, Imbalance in intestinal microbial flora will lead to an immune reaction that leads to chronic inflammation (eg. Inflammatory bowel disease), obesity is known to be the cause for chronic inflammation due to overweight the accumulation of fat in adipose tissuse can lead to a chronic inflammatory response. Infectious agents are a known cause for the chronic inflammation.

Question 4.) Answer is All the answers are correct.

Because Myasthenia gravis is an autoimmune disorder, the development of antibodies(triggered by antibodies) are targeted to the muscle end plate at the neuromuscular junction affecting the activity of Acetylcholine leading to destruction if muscle cells causing weakness (primary involved muscles are eyelid, ocular, Pharyngeal and facial muscles). Later limbs and respiratory muscles are affected in this condition.

Thankyou...