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Most medically used antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why do you think...

Most medically used antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why do you think the cytoplasmic (cell) membrane would be a POOR target for antibacterial medications?
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The cytoplamic membrane of prokaryotes (bacteria) is structurally similar to that of eukaryotes (humans) i.e . both consist of a phospholipid bilayer. Therefore antibiotics that affect the prokaryotic cells will also adversely affect the eukaryotic cells as well. Therefore, the cytoplasmic membrane serves a poor target for antibacteria action. On the other hand, peptidoglycan is only present in prokaryotes and not in eukaryotes. The prokaryotes possess a 70S ribosome whereas the eukaryotes possess a 80 S ribosome.

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